宋亚囝： 博士，天津科技老员工物工程学院副教授，工程生物学教研室主任，中国生物发酵产业协会淀粉糖分会、多元醇分会理事
主要研究方向：
· 微生物多糖代谢及相关酶资源的功能研究与开发
· 益生菌及益生元的生理功能与应用研究
教育及科研经历：
· 2017.9-2018.9，美国明尼苏达大学，食品科学与营养系，访问学者
· 2013.7至今，伟德BETVLCTOR，伟德BETVLCTOR，讲师、副教授
· 2011.5-2011.8，德国汉堡工业老员工物过程与生物系统研究所，访问学者
· 2006.9–2013.6，中国科学院微生物研究所，微生物资源前期开发国家重点实验室，理学博士
· 2002.9–2006.6，山东大学生命科学学院，生物工程专业，工学学士
承担科研任务：
· 企业横向课题，饲用微生态制剂开发，山东泰山生力源集团，2021.11-2022.11，主持
· 天津科技发展战略研究计划，18JCZDJC33800，植物乳杆菌CGMCC8198对HMG-CoA还原酶的转录调控及降血脂作用研究，2018.04-2021.03，参与
· 国家重点研发计划，2017YFD0400304，膳食功能因子与营养健康食品的靶向健康干预作用分析与评价，2017.07-2021.06，子课题负责人
· 国家自然科学基金项目，31671842，液体发酵过程发菜多糖生物合成的调控机制研究，2017.01 -2020.12，参与
· 国家自然科学基金项目，31601409，大兴安岭多年冻土来源的低温木糖苷酶AX543冷适应机制的研究，2017.01-2019.12，参与
· 国家自然科学基金项目，31400031，寡糖转运在嗜碱芽孢杆菌 N16-5 半纤维素利用中的作用研究，2015.01-2017.12，主持
· 天津市科技计划项目，14JCZDJC33200，L. caser HZ1新型降压肽的鉴定及其分子育种研究，2014.01-2017.12，参与
发表论文：
1. Yajian Song#*, Huitao Shen#, Tingting Liu, Bingju Pan, Sanduni De Alwis, Wanyi Zhang, Xuegang Luo, Zhongyuan Li, Nan Wang, Wenjian Ma, Tongcun Zhang*. Effects of Three Different Mannans on Obesity and Gut Microbiota of High-fat Diet-fed C57BL/6J Mice. Food & Function, 2021, 12(10):4606-4620
2. Wenting Liu#, Cuiping Ma#, Weidong Liu#, Yingying Zheng, Chun-Chi Chen, Ailing Liang, Xuegang Luo, Zhongyuan Li, Wenjian Ma, Yajian Song*, Rey-Ting Guo*, Tongcun Zhang*. Functional and structural investigation of a novel β-mannanase BaMan113A from Bacillus sp. N16-5. International Journal of Biological Macromolecules. 2021, 182: 899-909
3. 潘炳菊，张宛怡，申会涛，刘婷婷，李中媛，罗学刚，宋亚囝*.甘露寡糖分离纯化研究进展. 中国生物工程杂志. 2020, 40(11):90-95
4. 马翠萍，刘朵朵，潘炳菊，申会涛，宋亚囝*. 来源于嗜碱芽孢杆菌 N16-5甘露聚糖利用基因簇的乙酰酯酶 AesA的克隆及性质分析. 中国生物工程杂志. 2020, 40(3):65-71
5. Yajian Song#*, Wenyuan Sun#, Yanli Fan#, Yanfen Xue, Duoduo liu, Cuiping Ma, Wenting Liu, Wesley Mosher, Xuegang Luo, Zhongyuan Li, Wenjian Man, Tongcun Zhang*. Galactomannan Degrading Enzymes from the Mannan Utilization Gene Cluster of Alkaliphilic Bacillus sp. N16‑5 and Their Synergy on Galactomannan Degradation. Journal of Agricultural and Food Chemistry. 2018, 66:11055-11063.
6. Yajian Song*, Duoduo Liu, Mengya Liu, Haixu Yang, Yanli Fan, Wenyuan Sun, Yanfen Xue, Tongcun Zhang, Yanhe Ma. Transcriptional Regulation of the Mannan Utilization Genes in the Alkaliphilic Bacillus sp. N16-5. FEMS Microbiology Letters. 2018, 365:fnx280
7. Yao Zhang, Yanli Fan, Haijie Hu, Haixu Yang, Xuegang Luo, Zhongyuan Li, Hao Zhou, Wenjian Ma, Yajian Song*, Tongcun Zhang. D-Tagatose Production by Lactococcus lactis NZ9000 Cells Harboring Lactobacillus plantarum L-Arabinose Isomerase. Indian Journal of Pharmaceutical Education and Research. 2017, 51:288-94
8. Wenyuan Sun, Yanli Fan, Jing Li, Gaoshaer Kayierhali, Xuejiao Liu, Yun Hao, Yirong Hou, Yajian Song*, Tongcun Zhang. Isolation and 16SrDNA Identification of Bacteria from Traditional Kazak Dairy Products. Advances in Applied Biotechnology. Lecture Notes in Electrical Engineering. 2017;444:803-9
9. Yajian Song, Jinshan Li, Shan Meng, Liang Yin, Yanfen Xue, Yanhe Ma*. A Novel Manno-Oligosaccharide Binding Protein Identified in Alkaliphilic Bacillus sp. N16-5 Is Involved in Mannan Utilization. PLoS One. 2016, 11:e0150059.
10. Wen Du, Yajian Song, Mengya Liu, Haixu Yang, Yao Zhang, Yanli Fan, Xuegang Luo, Zhongyuan Li, Nan Wang, Hongpeng He, Hao Zhou, Wenjian Ma, Tongcun Zhang*. Gene Expression Pattern Analysis of a Recombinant Escherichia coli Strain Possessing High Growth and Lycopene Production Capability when Using Fructose as Carbon Source. Biotechnology Letters. 2016, 38:1571-1577
11. Junzhen Bai#, Yanjian Song#, Xuegang Luo, Haixu Yang, Wen Du, Tongcun Zhang*. Construction of L-tert-Leucine producing strain by expressing heterologous leucine dehydrogenase and formate dehydrogenase in Escherichia coli. Advances in Applied Biotechnology. Lecture Notes in Electrical Engineering. 2015;333:21-30
12. Yajian Song, Yanfen Xue, Yanhe Ma*. Global Microarray Analysis of Carbohydrate Use in Alkaliphilic Hemicellulolytic Bacterium Bacillus sp. N16-5. PLoS One. 2013, 8:e54090
联系方式：022-60601104 songyajian@tust.edu.cn
