赵冬菊，博士，天津科技老员工物工程学院讲师。
科研领域及方向
[1] 纳米生物材料构建及其在神经退行性疾病中的应用研究
[2] 天然产物活性分子及其衍生物的药理学研究
主要学术成果
先后发表各类科研论文6篇，授权国家发明专利2项。发表的主要学术论文有：
[1] Dongju Zhao#, Chao Tian#, Meng Cheng, Fan Yang, Chunxiao Tian, Yining Liu, Ziyao Chen, Gaoju Pang, Hui Shen*, Jin Chang*, Yan Dou*. Carrier-free quercetin nanomedicine blocks NLRP3 deubiquitination and TXNIP recruitment for Parkinson’s disease therapy. Chemical Engineering Journal, 2023, 464, 142697.
[2] Dongju Zhao, Yuqing Tang, Xinjun Suo, Chaonan Zhang, Yan Dou*, Jin Chang*. A dual-targeted multifunctional nanoformulation for potential prevention and therapy of Alzheimer’s disease. The Innovation, 2021, 2, 100160.
[3] Fan Yang#, Dongju Zhao#, Meng Cheng, Yining Liu, Ziyao Chen, Jin Chang*, and Yan Dou*.mTOR-mediated immunometabolic reprogramming nanomodulators enable sensitive switching of energy deprivation-induced microglial polarization for Alzheimer’s disease management. ACS Nano, 2023, 17(16),15724-15741.
[4] Yan Dou#,*, Dongju Zhao#, Fan Yang, Yuqing Tang, Jin Chang*. Natural phyto-antioxidant albumin nanoagents to treat advanced Alzheimer’s disease. ACS Applied Materials & Interfaces, 2021, 13(26), 30373-30382.
[5] Yan Dou#,*, Dongju Zhao#. Targeting emerging pathogenic mechanisms by natural molecules as potential therapeutics for neurodegenerative diseases. Pharmaceutics, 2022, 14(11), 2287.
[6] Yuqing Tang, Dongju Zhao, Fan Yang, Gaoju Pang, Zuhao Sun, Jin Chang*, Yan Dou*. Hsp90 co-chaperone degradation combined with antioxidation nanostrategy to rescue tauopathy-induced Alzheimer’s disease. Chemical Engineering Journal, 2022, 432, 134352.
申请和授权发明专利主要有：
[1] 一种靶向Aβ老年斑的普鲁士蓝纳米颗粒及其制备方法. 中国发明专利授权号：ZL201910217120.X.
[2] 普鲁士蓝纳米颗粒在制备预防、延缓或治疗神经系统退行性疾病药物中的应用. 中国发明专利授权号：ZL202010519012.0.
联系方式
办公地点：天津经济技术开发区第十三大街29号天津科技老员工物工程学院
邮政编码：300457
办公电话：022-60602948
传 真：022-60602298
Email：zhaodongju@tust.edu.cn
